| Registro completo |
| Provedor de dados: |
Biological Sciences
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| País: |
Brazil
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| Título: |
Effect of fermentation conditions on the production of hyaluronic acid by Streptococcus zooepidemicus ATCC 39920
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| Autores: |
Pan, Nicole Caldas
Vignoli, Josiane Alessandra
Baldo, Cristiani
Pereira, Hanny Cristina Braga
Silva, Rui Sérgio dos Santos Ferreira
Celligoi, Maria Antonia Pedrine Colabone
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| Data: |
2015-10-01
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| Ano: |
2015
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| Palavras-chave: |
Bioquímica de microrganismos physical factors
Nutritional factors
Glycosaminoglycans
Factorial design
Microbial production. Fermentação
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| Resumo: |
The production of hyaluronic acid by Streptococcus zooepidemicus ATCC 39920 with varying rates of pH (6.0, 7.0, 8.0), temperature (34; 37; 40°C), agitation (100, 150, 200 rpm), glucose (10, 20, 30 g L-1) and yeast extract concentration (10, 20, 30 g L-1) was evaluated by statistical approaches. The best conditions for the production of hyaluronic acid was pH 8.0, 37°C and 100 rpm in a medium containing 30 g L-1 glucose and yeast extract, for a production of 0.787 g L-1. Temperature, pH and yeast extract were significant variables (p < 0.05). Yeast extract and pH had a positive effect on the production of the polymer. Lactate, formate and acetate synthesis were also analyzed. Current assay showed the feasibility of statistical tools to optimize the physical and nutritional parameters for the production of hyaluronic acid and the improvement of the fermentation process.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/28176
10.4025/actascibiolsci.v37i4.28176
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| Editor: |
Universidade Estadual De Maringá
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| Relação: |
http://periodicos.uem.br/ojs/index.php/ActaSciBiolSci/article/view/28176/pdf_80
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| Formato: |
application/pdf
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| Fonte: |
Acta Scientiarum. Biological Sciences; v. 37, n. 4 (2015); 411-417
Acta Scientiarum. Biological Sciences; v. 37, n. 4 (2015); 411-417
1807-863X
1679-9283
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